Ibogaine clinical trials in the registry
Data as of 11 October 2026. Source: ClinicalTrials.gov records held by PsychoactiveMap, refreshed from a reviewed snapshot.
Ibogaine is a naturally occurring compound found in the root bark of the African shrub Tabernanthe iboga. This page summarises registered studies whose registry records mention it, using PsychoactiveMap's copy of the ClinicalTrials.gov registry.
Educational information, not medical advice. A registry listing is not evidence of safety, benefit or results, and it is not a recommendation. PsychoactiveMap does not recruit, screen or refer participants. Status and other details are copied from the registry and can be out of date, so check the registry record and speak to a qualified health professional before any decision. Read the full disclaimer.
At a glance
- 9 registered Ibogaine studies are counted on this page.
By registry status
| Status | Studies | Share |
|---|---|---|
| Recruiting | 1 | 11% |
| Active, not recruiting | 2 | 22% |
| Completed | 5 | 56% |
| Withdrawn | 1 | 11% |
By phase
| Phase | Studies | Share |
|---|---|---|
| Phase 1 | 3 | 33% |
| Phase 2 | 3 | 33% |
| Not reported | 3 | 33% |
Countries
Country is taken from the study's linked research site. 0 of 9 records have no country on file. The top 5 countries are shown.
| Country | Studies | Share |
|---|---|---|
| United States | 4 | 44% |
| United Kingdom | 2 | 22% |
| Australia | 1 | 11% |
| Brazil | 1 | 11% |
| Spain | 1 | 11% |
When studies started
| Start year | Studies |
|---|---|
| 2024 to 2026 | 3 |
| 2020 to 2023 | 6 |
Study design
- 6 interventional and 3 observational studies.
- Median planned or actual enrolment is 41 participants (range 9 to 116, across 8 records that report it).
Topics named in study titles
A keyword match on registered titles, so one study can appear under more than one topic and a study can be missed. It describes what titles mention, nothing more.
| Topic | Studies |
|---|---|
| Other substance use | 2 |
| Healthy volunteers | 2 |
| Alcohol use | 1 |
Most recently started studies
The 9 studies with the latest start dates, shown newest first. The order is not a ranking and says nothing about quality. Each ID links to its own ClinicalTrials.gov record, which has the eligibility criteria and contacts.
| Registry ID | Title as registered | Status | Phase | Country | Start |
|---|---|---|---|---|---|
| NCT07226570 | Mapping Ibogaine Neural Dynamics in Opioid Use Disorder | Recruiting | Not reported | United States | 2025-09 |
| NCT06810765 | Trifecta Research Study | Withdrawn | Phase 2 | United States | 2025-09 |
| NCT06480981 | Multiple Ascending Dose Noribogaine PK/PD in Healthy Volunteers | Completed | Phase 1 | United Kingdom | 2024-06 |
| NCT03380728 | Ibogaine in the Treatment of Alcoholism: an Open-label Escalating-dose Trial | Completed | Phase 2 | Brazil | 2022-10 |
| NCT07717866 | Trifecta Research Study | Active, not recruiting | Not reported | United States | 2022-08 |
| NCT04313712 | Pre-post Evaluation of the Safety and Efficacy of Ibogaine-Magnesium Therapy in Veterans With Repeated Blast Exposure | Active, not recruiting | Not reported | United States | 2021-11 |
| NCT05029401 | A Study of Oral Ibogaine in Opioid Withdrawal | Completed | Phase 1 | United Kingdom | 2021-04 |
| NCT04003948 | Preliminary Efficacy and Safety of Ibogaine in the Treatment of Methadone Detoxification | Completed | Phase 2 | Spain | 2020-10 |
| NCT04292197 | A Study to Assess 18-Methoxycoronaridine (18-MC HCl) in Healthy Volunteers | Completed | Phase 1 | Australia | 2020-04 |
About this data
Compound tags come from automated matching of the registry search term and have not been checked record by record. Counts are of registered studies, not of people, results or approvals.
Other substance hubs
Psilocybin | MDMA | LSD | DMT | 5-MeO-DMT | Ayahuasca | Ketamine
Registry status hubs
Recruiting | Not yet recruiting | Active, not recruiting | Enrolling by invitation | Completed | Terminated | Suspended | Withdrawn
Phase hubs
Early Phase 1 | Phase 1 | Phase 2 | Phase 3 | Phase 4 | Phase not applicable